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发布日期:2023-02-22
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胡鹏 教授

鹏,博士



954567红宝石教授、博士生导师

水产种质资源发掘与利用教育部重点实验室主任  

上海海洋大学青年教师工作委员会主任

国家青年人才计划入选者

邮箱phu@shou.edu.cn 

学术网页: https://scholar.google.com/citations?hl=en&user=c9x6MQcAAAAJ

ORICD: 0000-0002-0017-1948


实验室网页www.hulabshou.cn


教育和学习经历

美国宾夕法尼亚大学,美国宾州费城市

· 2016年4月- 202112   博士后, 医学院

· 合作导师:Hao Wu教授

 

上海海洋大学,中国上海市

· 2014年2月- 2016年4月    博士后, 生命学院

· 合作导师:陈良标教授

 

中国科学院遗传与发育生物学研究所,中国北京市

· 2009年9月- 2014年1月    理学博士,生物信息学

· 导师:陈良标教授

 

中国农业大学,中国北京市

· 20079月- 2009年7月    农学硕士,动物遗传育种与繁殖

· 导师:王爱国教授

 

华中农业大学,中国湖北省武汉市

· 2003年9月- 2007年7月    农学学士,动物科学

 

 

工作经历

上海海洋大学,中国上海市

· 202112- 至今          教授、博士生导师, 水产与生命学院

研究方向

1. 单细胞多组学技术挖掘主效基因及分子机制

2. 抗病抗逆分子育种

3. 病原现场快速分子检测技术开发

 

学术兼职

国际干细胞协会会员

Frontiers in Genetics, 客座副主编, 2020/10

Molecular Biology & Evolution, Fish and Shellfish Immunology, JWAS等期刊审稿人

 

获奖情况

鱼类抗冻蛋白基因的起源和低温适应的分子发育机制研究,2021教育部高等学校科学研究优秀成果奖(科学技术)一等奖(排名:12/12)

 

发表论文及预印本

2024

Sweat gland development requires an eccrine dermal niche and couples two epidermal programs.

Dingwall HL, Tomizawa RR, Aharoni A, Hu P, Qiu Q, Kokalario B, Martinez SM, Donahue JC, Aldea D, Mendoza M, Glass I, BDRL, Wu H, Kamberov YG

Developmental Cell  PMID: 38096824

 

2023

Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects.

Fabyanic E*, Hu P*(共同第一), Qiu Q*, Wang T, Berrios KN, Flournoy J, Connolly DR, Zhou Z, Kohil RM, Wu H

Nature Biotechnology  PMID: 37640946

 

2022

Molecular landscapes of human hippocampal immature neurons across lifespan.

Zhou Y, Su Y, Li S, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaena A…, Ming G, Song H

Nature  PMID: 35794479

Neuronal Yin Yang1 in the prefrontal cortex regulates transcriptional and behavioral responses to chronic stress in mice. 

Kwon DY, Xu B*, Hu P*, Zhao YT, Beagan JA, Nofziger JH, Cui Y, Xu B, Zaitseva D, Phillips-Cremins JE, Blendy JA, Wu H, Zhou Z

Nature Communications  PMID: 35013139

Population genomics of an icefish reveals mechanisms of glacier-driven adaptive radiation in Antarctic notothenioids.

Lu Y, Li W, Li Y, Zhai W, Zhou X,Wu Z, Jiang S, Liu T, Wang H, Hu R, Zhou Y, Hu P, Guan G, Xu Q, Canario AVM, Chen L

BMC Biology  PMID: 36224580

 

2020

Massively parallel and time-resolved single-cell RNA sequencing with scNT-Seq.

Qiu Q*, Hu P*(共同第一), Qiu X, Govek KW, Camara PG, Wu H

Nature Methods  PMID: 32868927

Single cell transcriptomic analysis of the adult mouse pituitary reveals a novel multi-hormone cell cluster and physiologic demand-induced lineage plasticity.

Ho Y*, Hu P*(共同第一), Peel MT, Chen S, Camara PG, Epstein DJ, Wu H, Liebhaber SA

Protein & Cell  PMID: 32193873

The vertebrate- and testis- specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding

Hao H, Shi B, Zhang J, Dai A, Li W, Chen H, Ji W, Gong C, Zhang C, Li J, Chen L, Yao B, Hu P, Yang H, Brosius J, Lai S, Shi Q & Deng C

Molecular Biomedicine  PMID: 36050562

MiR-202-3p determines embryo viability during mid-blastula transition

Hu R, Xu Y, Han B, Chen Y, Li W, Guan G, Hu P, Zhou Y, Xu Q, Chen L

Frontiers in Cell and Developmental Biology  PMID: 36003151

 

2019

Transcriptomic responses to low temperature stress in the Nile tilapia, Oreochromis niloticus.

Zhou T, Gui L, Liu M, Li W, Hu P, Duarte DFC, Niu H, Chen L

Fish & Shellfish Immunology  PMID: 30408600

 

2018

Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts.

Hu P*, Liu J*, Zhao J*, Wilkins BJ, Lupino K, Wu H, Pei L

Genes & Development  PMID: 30254108

Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase.

Schutsky EK, DeNizio JE, Hu P, Liu MY, Nabel CS, Fabyanic EB, Hwang Y, Bushman FD, Wu H, Kohli RM

Nature Biotechnology  PMID: 30295673

GC bias lead to increased small amino acids and random coils of proteins in cold-water fishes.

Zhang D, Hu P, Liu T, Wang J, Jiang S, Xu Q, Chen L

BMC Genomics  PMID: 29720106

 

2017

Dissecting Cell-Type Composition and Activity-Dependent Transcriptional State in Mammalian Brains by Massively Parallel Single-Nucleus RNA-Seq.

Hu P*, Fabyanic E*, Kwon DY, Tang S, Zhou Z, Wu H

Molecular Cell  PMID: 29220646

Genetic Adaptation of Schizothoracine Fish to the Phased Uplifting of the Qinghai–Tibetan Plateau.

Zhang D*, Yu M*, Hu P*(共同第一), Peng S, Liu Y, Li W, Wang C, He S, Zhai W, Xu Q, Chen L

G3: Genes|Genomes|Genetics  PMID: 28209761

Divergent adaptation to Qinghai-Tibetan Plateau implicated from transciptome study of Gymnocypris dobula and Schizothorax nukiangensis.

Yu M, Zhang D, Hu P, Peng S, Li W, He S, Zhai W, Xu Q, Chen L

Biochemical Systematics and Ecology

 

2016

Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish.

Hu P, Liu M, Liu Y, Wang J, Zhang D, Niu H, Jiang S, Wang J, Zhang D, Han B, Xu Q, Chen L

Scientific Reports  PMID: 27356472

Neofunctionalization of zona pellucida proteins enhances freeze-prevention in the eggs of Antarctic notothenioids.

Cao L, Huang Q, Wu Z, Cao D, Ma Z, Xu Q, Hu P, Fu Y, Shen Y, Chan J, Zhou C, Zhai W, Chen L

Nature Communications  PMID: 27698404

 

2015

Global identification of the genetic networks and cis-regulatory elements of the cold response in zebrafish.

Hu P, Liu M, Zhang D, Wang J, Niu H, Liu Y, Wu Z, Han B, Zhai W, Shen Y, Chen L

Nucleic Acids Research  PMID: 26227973

Evolutionary suppression of erythropoiesis via the modulation of TGF-β signalling in an Antarctic icefish.

Xu Q, Cai C, Hu X, Liu Y, Guo Y, Hu P, Chen Z, Peng S, Zhang D, Jiang S, Wu Z, Chan J, Chen L

Molecular Ecology  PMID: 26268413

 

实验室成员

实验室位于海洋科技大楼1018

工作人员:

黄松钱副教授、徐淑坦副教授、吴智超工程师、刘明丽博士后、刘涵宇科研助理

研究生:

张晓雯博二、翟雪博二、李新闻博一、魏朝广博一、李晓龙博一(兰州大学联合培养)、程江博博一(兰州大学联合培养)

焦荷硕三、徐元硕三、彭铭健硕二、谢宏帅硕二、张明皓硕二、赵文欣硕二、曹瑞萌硕二

占思瑶研一、朱江浩研一王文婷研一祁婧婷研一严晨瑜研一

王冰倩本四、徐逸程本三、张钧睿本三、罗婧一本三、常诚本一、李鑫阳本一


更新于2024-03-01